Cannabidiol Reduces Cigarette Consumption in Tobacco Smokers: Preliminary Findings
Article in Addictive Behaviors, 38 | Read Full Study
Highlights: the study examined whether cannabidiol could impact on cigarette consumption. Researchers found the following:
- Ad hoc use of CBD but not placebo reduced cigarette consumption over a week;
- Drugs that alter the endocannabinoid system may be effective treatments for nicotine addiction.
The Study:
The role of the endocannabinoid system in nicotine addiction is being increasingly acknowledged.
We conducted a pilot, randomized double blind placebo controlled study set out to assess the impact of the ad-hoc use of cannabidiol (CBD) in smokers who wished to stop smoking.
Twenty-four (24) smokers were randomized to receive an inhaler of CBD (n = 12) or placebo (n = 12) for one week, they were instructed to use the inhaler when they felt the urge to smoke.
The Results:
Over the treatment week, placebo treated smokers showed no differences in number of cigarettes smoked. In contrast, those treated with CBD significantly reduced the number of cigarettes smoked by ~ 40% during treatment.
Results also indicated some maintenance of this effect at follow-up.
These preliminary data, combined with the strong preclinical rationale for use of this compound, suggest CBD to be a potential treatment for nicotine addiction that warrants further exploration.
Read the full study details | View PDF
Credits: Celia J.A. Morgan, Ravi K. Das, Alyssa Joye, H. Valerie Curran, Sunjeev K. Kamboj.
Clinical Psychopharmacology Unit, University College London, London, UK.
Published in: Addictive Behaviors, 38 (2013) – An International Journal
Reference links: ScienceDirect | Document Online
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